占文俊

发布者:张怡茹发布时间:2021-12-09浏览次数:3447

占文俊,副研究员,硕士生导师。

201812月毕业于苏州大学材料与化学化工学部,获高分子化学与物理博士学位。20179月至20189月在美国布兰迪斯大学化学系访问学习。2019年加入beplay网页版登录工作。主要从事生物医药和生物成像等领域的研究。至今,以第一作者/通讯作者(含共同)在Adv. Mater.Angew. Chem., Int. Ed.J. Am. Chem. Soc.Nat. Commun.Adv. Sci.Adv. Funct. Mater.等国内外学术期刊发表学术论文18篇,其中IF>1010篇;共发表SCI论文40余篇,总被引1500余次,H因子21。主持国家自然科学基金青年科学基金项目1项;以课题骨干身份参与国家重点研发计划、国自然重点/面上项目等国家级项目多项。

 

研究方向:

纳米药物、生物成像、多肽自组装、超分子水凝胶。

 

招生信息:

优秀本科生不限;硕士研究生2-3/年。欢迎各位感兴趣的同学联系攻读硕士学位,包括但不限于生物医学工程、分析化学、高分子、有机化学、药学等!

邮箱: wjzhan@seu.edu.cn;课题组网站: /lianglab/

 

科研项目:

1.国家自然科学基金青年基金项目,串联酶控自组装和药物缓释用于肿瘤的自噬增强型化疗研究,2022-012024-1230万元,在研,主持

2.中央高校基本科研业务费,智能肿瘤低温热疗技术,2242020k300092020-012020-1220万,已结题,主持

3.科技部,国家重点研发计划基础科研条件与重大科学仪器设备研发专项,2023YFF0724100,多元素磁共振高灵敏成像纳米造影剂设计制备及应用示范,2023-112026-10 1000万元,在研,研究骨干

4.江苏省科技厅,前沿引领技术基础研究重大专项,BK20232007,用于耳聋防治的生物大分子药物精准递送,2023.10-2026.09500万元,在研,研究骨干

5.国家自然科学基金委员会,重点项目,22234002,基于组装/解组装策略的活体成像,2023-012027-12280万元,在研,研究骨干

 

学术奖励:

1.2023年,中国发明协会发明创业奖创新奖二等奖(排第2

2.2021年,南京市留学人员科技创新项目择优资助计划

 

代表性成果:

1.Han Yin, Yue Hua, Songwei Feng, Yi Xu, Yue Ding, Sicong Liu, Dongsheng Chen, Furong Du, Gaolin Liang*, Wenjun Zhan*, and Yang Shen*. In Situ Nanofiber Formation Blocks AXL and GAS6 Binding to Suppress Ovarian Cancer Development. Advanced Materials 2024, 36(21), 202308504. (Editor's Choice, Q1IF:29.4)

2.Wenjun Zhan, Lingling Xu, Zhiyu Liu, Xiaoyang Liu, Ge Gao, Tiantian Xia, Xiaotong Cheng, Xianbao Sun, Fu-Gen Wu, Qian Yu, and Gaolin Liang*. Tandem Guest-Host-Receptor Recognitions Precisely Guide Ciprofloxacin to Eliminate Intracellular Staphylococcus aureus. Angewandte Chemie International Edition2023, 62(32), e202306427. (Hot PaperQ1IF16.6)

3.Lingling Xu, Hang Gao, Wenjun Zhan, Yu Deng, Xiaoyang Liu, Qiaochu Jiang, Xianbao Sun, Jing-Juan Xu, and Gaolin Liang*. Dual Aggregations of a Near-Infrared Aggregation-Induced Emission Luminogen for Enhanced Imaging of Alzheimer's Disease. Journal of the American Chemical Society2023, 145(50), 27748–27756. (Q1IF15.0)

4.Qiaochu Jiang, Wenjun Zhan, Xiaoyang Liu, Lin Bai, Manli Wang, Ying Xu, and Gaolin Liang*. Assembly Drives Regioselective Azide-Alkyne Cycloaddition Reaction. Nature Communications2023, 14(1), 3935. (Q1IF16.6)

5.Wenjun Zhan, Gao Ge, Zhiyu Liu, Xiaoyang Liu, Lingling Xu, Manli Wang, Xianbao Sun, and Gaolin Liang*. Enzymatic Self-Assembly of Adamantane-Peptide Conjugate for Combating Staphylococcus aureus Infection. Advanced Healthcare Materials 2023, 12(18), 2203283. (Q1IF10.0)

6.Yue Hua, Han Yin, Xiaoyang Liu, Jinbing Xie, Wenjun Zhan*, Gaolin Liang* and Yang Shen*. Salt-Inducible Kinase 2-Triggered Release of Its Inhibitor from Hydrogel to Suppress Ovarian Cancer Metastasis. Advanced Science 2022, 9(22), 2202260. (Q1IF:15.1)

7.Lingling Xu, Nanhui Liu, Wenjun Zhan, Yu Deng, Zhaoxiao Chen, Xiaoyang Liu, Ge Gao, Qian Chen, Zhuang Liu, and Gaolin Liang*. Granzyme B Turns Nanoparticle Fluorescence “On” for Imaging Cytotoxic T Lymphocyte Activity in Vivo. ACS Nano2022, 16(11), 19328-19334. (Q1IF17.1)

8.Yu Deng, Wenjun Zhan*, and Gaolin Liang*. Intracellular Self‐Assembly of Peptide Conjugates for Tumor Imaging and Therapy.Advanced Healthcare Materials2021, 10(1), 2001211. (Invited Review, Q1IF10.0)

9.Wenjun Zhan, Yangcui Qu, Ting Wei, Changming Hu, Yue Pan, Qian Yu*, and Hong Chen*. Sweet Switch: Sugar-Responsive Bioactive Surfaces Based on Dynamic Covalent Bonding. ACS Applied Materials & Interfaces2018, 10(13), 10647-10655. (Q1IF9.5)

10.Wenjun Zhan, Xiujuan Shi, Qian Yu*, Zhonglin Lyu, Limin Cao, Hui Du, Qi Liu, Xin Wang, Gaojian Chen, Dan Li, John L. Brash and Hong Chen*. Bioinspired Blood Compatible Surface Having Combined Fibrinolytic and Vascular Endothelium-Like Properties via a Sequential Coimmobilization Strategy. Advanced Functional Materials2015, 25(32), 5206-5213. (Q1IF19.0)